DMGDH polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61706
Background:
DMGDH (dimethylglycine dehydrogenase), also known as ME2GLYDH or DMGDHD, is an 866 amino acid mitochondrial protein that plays a role in choline catabolism by catalyzing the demethylation of dimethylglycine to form sarcosine. Existing as a monomer that belongs to the gcvT family, DMGDH utilizes flavin adenine dinucleotide (FAD) and folate as cofactors. DMGDH is encoded by a gene that maps to human chromosome 5q14.1, defects of which are the cause of DMGDH deficiency (DMGDHD). Patients with DMGDHD experience muscle fatigue, have a fish-like odor and excrete an elevated level of N,N-dimethylglycine (DMG) in urine.
Alternative Name:
Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH, DMGDH
Application Dilution: WB: 1:500~1:1000
Specificity: DMGDH polyclonal antibody detects endogenous levels of DMGDH protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 810-860 of Human DMGDH.
MW: ~ 96 kDa
Swis Prot.: Q9UI17
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
DMGDH (dimethylglycine dehydrogenase), also known as ME2GLYDH or DMGDHD, is an 866 amino acid mitochondrial protein that plays a role in choline catabolism by catalyzing the demethylation of dimethylglycine to form sarcosine. Existing as a monomer that belongs to the gcvT family, DMGDH utilizes flavin adenine dinucleotide (FAD) and folate as cofactors. DMGDH is encoded by a gene that maps to human chromosome 5q14.1, defects of which are the cause of DMGDH deficiency (DMGDHD). Patients with DMGDHD experience muscle fatigue, have a fish-like odor and excrete an elevated level of N,N-dimethylglycine (DMG) in urine.
Alternative Name:
Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH, DMGDH
Application Dilution: WB: 1:500~1:1000
Specificity: DMGDH polyclonal antibody detects endogenous levels of DMGDH protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 810-860 of Human DMGDH.
MW: ~ 96 kDa
Swis Prot.: Q9UI17
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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