DNM1L polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms: DLP1, DRP1, DVLP, DYMPLE, EMPF, EMPF1, HDYNIV

Cellular Location: Cytoplasm Cytoplasmic vesicle Endomembrane system Golgi apparatus Membrane Mitochondrion outer membrane Peripheral membrane protein Peroxisome clathrin-coated pit cytosol secretory vesicle synaptic vesicle membrane

Immunogen:
Recombinant protein of human DNM1L

Gene Symbol: DNM1L

Gene ID: 10059

Swiss prot: O00429

Calculated MW: 82kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.