DSCR5 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6322a
Background:
DSCR5 is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. DSCR5 is an N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). The DSCR5 gene is located in the Down Syndrome critical region (DSCR) on chromosome 21 and is a candidate for the pathogenesis of Down syndrome.
Other Names:
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P, Down syndrome critical region protein 5, Down syndrome critical region protein C, Phosphatidylinositol-glycan biosynthesis class P protein, PIG-P, PIGP, DCRC, DSCR5, DSCRC
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6322a was selected from the N-term region of human DSCR5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PIGP (HGNC:3046)
Gene ID: 51227
Primary Accession: P57054
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
DSCR5 is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. DSCR5 is an N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). The DSCR5 gene is located in the Down Syndrome critical region (DSCR) on chromosome 21 and is a candidate for the pathogenesis of Down syndrome.
Other Names:
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P, Down syndrome critical region protein 5, Down syndrome critical region protein C, Phosphatidylinositol-glycan biosynthesis class P protein, PIG-P, PIGP, DCRC, DSCR5, DSCRC
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6322a was selected from the N-term region of human DSCR5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PIGP (HGNC:3046)
Gene ID: 51227
Primary Accession: P57054
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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