ECHA Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes the alpha subunit of the mitochondrial trifunctional protein| which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits| with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction, Tags & cell markers

Synonyms: ECHA, Trifunctional enzyme subunit alpha, mitochondrial, 78 kDa gastrin-binding protein, TP-alpha) [Includes: Long-chain enoyl-CoA hydratase, EC 4.2.1.17, Long chain 3-hydroxyacyl-CoA dehydrogenase, EC 1.1.1.211,

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year