EMC8 Polyclonal Antibody

Background:
COX4NB (Neighbor of COX4) is a 210 amino acid protein encoded by the human gene COX4NB. COX4NB belongs to the UPF0172 (NOC4) family and is found on chromosome 16, adjacent to the gene that encodes COX4. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene which encodes a critical CREB binding protein. Crohn’s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other auto-immune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Research Area: Cell Biology

Synonyms:
C16orf2, C16orf4, COX4 neighbor, COX4, neighbor of, COX4AL, Cox4nb, CX4NB, ER membrane protein complex subunit 8, FAM158B, family with sequence similarity 158, member B, Neighbor of COX4, NOC4, Protein FAM158B

Immunogen: Recombinant protein of human EMC8

Swissprot: O43402
Gene Accession: BC001472

Calculated MW: 24 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-107509/sc-98311