EPOR Blocking Peptide (C-term)

Background:
Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

Other Names:
Erythropoietin receptor, EPO-R, EPOR

Target/Specificity:
The synthetic peptide sequence is selected from aa 470-484 of HUMAN EPOR

Gene Name: EPOR {ECO:0000303|PubMed:2163695, ECO:0000312|HGNC:HGNC:3416}

Gene ID: 2057
Primary Accession: P19235
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.