ERCC2 polyclonal, anti-human, mouse

Background:
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms: COFS2, EM9, TFIIH, TTD, TTD1, XPD

Cellular Location: Cytoplasm Nucleus cytoskeleton spindle

Immunogen:
Recombinant protein of human ERCC2

Gene Symbol: ERCC2

Gene ID: 2068

Swiss prot: P18074

Calculated MW: 87kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.