Exostosin-1 Peptide
€100.00
In stock
SKU
350499
Protein Family: Enzymes
Pathway and Disease: Cancers, Glycan Biosynthesis and Metabolism
Alternate Names: Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Putative tumor suppressor protein EXT1; Multiple exostoses protein 1; EXT1
Accession No.: Q16394, NP_000118
Description:
Exostosin-1 (EXT1) is a glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. EXT1 is a tumor suppressor. Defects in EXT1 are the cause of multiple exostoses disorders, i.e. skeletal deformities and bone tumors.
Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 2150.5 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200137 is selected from a sequence within the C-term region of human Exostosin-1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C92H160N30O27S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Pathway and Disease: Cancers, Glycan Biosynthesis and Metabolism
Alternate Names: Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Putative tumor suppressor protein EXT1; Multiple exostoses protein 1; EXT1
Accession No.: Q16394, NP_000118
Description:
Exostosin-1 (EXT1) is a glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. EXT1 is a tumor suppressor. Defects in EXT1 are the cause of multiple exostoses disorders, i.e. skeletal deformities and bone tumors.
Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 2150.5 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200137 is selected from a sequence within the C-term region of human Exostosin-1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C92H160N30O27S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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