FA58A rabbit polyclonal, anti-human, mouse, rat

Backgroud: Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008],disease:Defects in FAM58A are the cause of toe syndactyly, telecanthus, and anogenital and renal malformations (STAR) [MIM:300707]; also known as STAR syndrome or syndactyly with renal and anogenital malformations.,function:May have a role in cell proliferation.,similarity:Belongs to the cyclin family. Cyclin-like FAM58 subfamily.,subunit:Interacts with SALL1.,

Gene Name: FAM58A

Gene ID: 92002

SwissProt ID: Q8N1B3

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.