FAM13B Polyclonal Antibody

Background:
FAM13B is a 915 amino acid protein that is encoded by a gene that maps to human chromosome 5. With 181 million base pairs encoding around 1, 000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Research Area: Cancer, Cell biology, Signal transduction

Synonyms:
ARHGAP49, C5orf5, FA13B, Fam13b, FAM13B1, Family with sequence similarity 13 member B, Family with sequence similarity 13, member B1, GAP-like protein N61, KHCHP, N61, Protein FAM13B

Immunogen: Synthetic peptide of human FAM13B

Swissprot: Q9NYF5
Gene Accession: NP_057687

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-137459/sc-137458