FH/Fumarase polyclonal, anti-human, mouse, rat

Background:
Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate in the mitochondria. Fumarase deficiency is caused by a mutation in the fumarase gene in humans. Fumarase deficiency is one of the few known deficiencies of the Krebs cycle or tricarboxylic acid cycle, the main enzymatic pathway of cellular aerobic respiration.

Synonyms: FMRD, HLRCC, LRCC, MCL, MCUL1

Cellular Location: Cytoplasm Mitochondrion

Immunogen:
Recombinant Protein

Gene Symbol: FH/Fumarase

Gene ID: 2271

Swiss prot: P07954

Calculated MW: 50kDa

Recommended dilution:
WB 1:1000-2000, IHC 1:100-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.