FH polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7665
Background:
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Alternative Name:
FH, Fumarase, Fumarate hydratase, Fumarate hydratase mitochondrial, Fumarate hydratase, mitochondrial, FUMH_HUMAN, HLRCC, LRCC, MCL, MCUL 1, MCUL1, MS709, Multiple hereditary cutaneous leiomyomata,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: FH polyclonal antibody detects endogenous levels of FH protein.
Immunogen:
Recombinant full length Human FH.
MW: ~54 kDa
Swis Prot.: P07954
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Alternative Name:
FH, Fumarase, Fumarate hydratase, Fumarate hydratase mitochondrial, Fumarate hydratase, mitochondrial, FUMH_HUMAN, HLRCC, LRCC, MCL, MCUL 1, MCUL1, MS709, Multiple hereditary cutaneous leiomyomata,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: FH polyclonal antibody detects endogenous levels of FH protein.
Immunogen:
Recombinant full length Human FH.
MW: ~54 kDa
Swis Prot.: P07954
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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