FKTN Polyclonal Antibody

Background:
The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.

Research Area: Cancer, Developmental biology, Tags & Cell Markers

Synonyms:
CMD1X, FCMD, FCMD gene, FKTN, FKTN, Fukutin, Fukuyama type congenital muscular dystrophy protein, Fukuyama-type congenital muscular dystrophy protein, LGMD2M, MDDGA4, MDDGB4, MDDGC4, MGC126857, MGC134944, MGC134945, MGC138243, OTTHUMP00000021841, patient fukutin

Immunogen: Synthetic peptide of human FKTN

Swissprot: O75072
Gene Accession: NP006722

Calculated MW: 54 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.08 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.