GALE polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8279
Background:
GALE, also known as galactowaldenase, UDP-galactose-4-epimerase or SDR1E1, is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness.
Alternative Name:
UDP-glucose 4-epimerase, Galactowaldenase, UDP-galactose 4-epimerase
Gene namesi
Name:GALE
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: GALE polyclonal antibody detects endogenous levels of GALE protein.
Immunogen:
Recombinant full length Human GALE.
MW: ~ 38 kDa
Swis Prot.: Q14376
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
GALE, also known as galactowaldenase, UDP-galactose-4-epimerase or SDR1E1, is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness.
Alternative Name:
UDP-glucose 4-epimerase, Galactowaldenase, UDP-galactose 4-epimerase
Gene namesi
Name:GALE
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: GALE polyclonal antibody detects endogenous levels of GALE protein.
Immunogen:
Recombinant full length Human GALE.
MW: ~ 38 kDa
Swis Prot.: Q14376
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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