GBA polyclonal, anti-human, rat

Background:
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Alternative Name:
Beta-GC, GBA, Acid beta glucosidase, Acid beta-glucosidase, Alglucerase, Beta glucocerebrosidase, BETA GLUCOSIDASE, ACID, Beta-glucocerebrosidase, betaGC, D glucosyl N acylsphingosine glucohydrolase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45, GBA, Gba protein, GBA1, GC, GCase, GCB, GLCM, GLUC, Glucocerebrosidase (alt.), Glucocerebrosidase, GLUCOCEREBROSIDASE PSEUDOGENE, Glucosidase beta, Glucosidase, beta, acid, Glucosidase, beta, acid (includes glucosylceramidase), Glucosylceramidase, Imiglucerase, Lysosomal glucocerebrosidase, OTTHUMP00000033992, OTTHUMP00000033993,

Application Dilution:
WB:1:1,000-1:5,000
IHC:1:50-1:200

Specificity: GBA polyclonal antibody detects endogenous levels of GBA protein.

Immunogen:
recombinant protein

MW: 60 kDa

Swiss-Prot: P04062(Human) EntrezGene:684536 (Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.