GNS Antibody (Center N189) Blocking Peptide
€363.00
In stock
SKU
AC-BP6574c
Background:
GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
Other Names:
N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6574c was selected from the Center region of human GNS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GNS
Gene ID: 2799
Primary Accession: P15586
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
Other Names:
N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6574c was selected from the Center region of human GNS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: GNS
Gene ID: 2799
Primary Accession: P15586
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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