GPC6 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP11674b
Background:
This gene belongs to the Ras oncogene family, whosemembers are related to the transforming genes of mammalian sarcomaretroviruses. The products encoded by these genes function insignal transduction pathways. These proteins can bind GTP and GDP,and they have intrinsic GTPase activity. This protein undergoes acontinuous cycle of de- and re-palmitoylation, which regulates itsrapid exchange between the plasma membrane and the Golgi apparatus.Mutations in this gene cause Costello syndrome, a diseasecharacterized by increased growth at the prenatal stage, growthdeficiency at the postnatal stage, predisposition to tumorformation, mental retardation, skin and musculoskeletalabnormalities, distinctive facial appearance and cardiovascularabnormalities. Defects in this gene are implicated in a variety ofcancers, including bladder cancer, follicular thyroid cancer, andoral squamous cell carcinoma. Multiple transcript variants, whichencode different isoforms, have been identified for this gene.
Other Names:
Glypican-6, Secreted glypican-6, GPC6
Gene Name: GPC6
Gene ID: 10082
Primary Accession: Q9Y625
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene belongs to the Ras oncogene family, whosemembers are related to the transforming genes of mammalian sarcomaretroviruses. The products encoded by these genes function insignal transduction pathways. These proteins can bind GTP and GDP,and they have intrinsic GTPase activity. This protein undergoes acontinuous cycle of de- and re-palmitoylation, which regulates itsrapid exchange between the plasma membrane and the Golgi apparatus.Mutations in this gene cause Costello syndrome, a diseasecharacterized by increased growth at the prenatal stage, growthdeficiency at the postnatal stage, predisposition to tumorformation, mental retardation, skin and musculoskeletalabnormalities, distinctive facial appearance and cardiovascularabnormalities. Defects in this gene are implicated in a variety ofcancers, including bladder cancer, follicular thyroid cancer, andoral squamous cell carcinoma. Multiple transcript variants, whichencode different isoforms, have been identified for this gene.
Other Names:
Glypican-6, Secreted glypican-6, GPC6
Gene Name: GPC6
Gene ID: 10082
Primary Accession: Q9Y625
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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