GRO-gamma human active recombinant protein

GRO-gamma human active recombinant protein

€295.00
In stock
SKU
600321
Catalog Number: 600321
Size: 0.01 mg
Datasheet
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Protein Family: Cytokines

Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction

Alternate Names: MIP-2 beta, CXCL3, GRO3Description:
Growth Regulated Proteins (GRO) are a group of three proteins, GRO-alpha, -beta and –gamma, that are encoded by three distinct genes. All 3 GRO proteins can bind to the same receptors, but with differing affinities, and stimulate a number of biological responses including chemotaxis, angiogenesis, and growth regulation. More specifically, GRO gamma (also called CXCL3), can act through chemokine receptor CXCR2 to promote monocyte migration and adhesion. Human GRO-gamma is produced in E.coli. Recombinant human GRO gamma is a non-glycosylated protein, containing 73 amino acids, with a molecular weight of 7.9 kDa.

Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.

Applications: E, WB

Application Notes:
The activity is determined by the ability to chemoattract human neutrophils at concentrations between 10-100 ng/mL. Specific activity: 1 x 10e5 units/mg

Accession No.: P19876

MW: 7865 Da

Sequence:
ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN

Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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