HADHB polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8487
Background:
This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described.
Alternative Name:
Trifunctional enzyme subunit beta, mitochondrial, TP-beta, TP-β, TPβ, 3-ketoacyl-CoA thiolase (EC:2.3.1.16), Acetyl-CoA acyltransferase, Beta-ketothiolase, HADHB, MSTP029
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: HADHB polyclonal antibody detects endogenous levels of HADHB protein.
Immunogen:
Recombinant full length Human HADHB.
MW: ~ 51kDa
Swis Prot.: P55084
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described.
Alternative Name:
Trifunctional enzyme subunit beta, mitochondrial, TP-beta, TP-β, TPβ, 3-ketoacyl-CoA thiolase (EC:2.3.1.16), Acetyl-CoA acyltransferase, Beta-ketothiolase, HADHB, MSTP029
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: HADHB polyclonal antibody detects endogenous levels of HADHB protein.
Immunogen:
Recombinant full length Human HADHB.
MW: ~ 51kDa
Swis Prot.: P55084
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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