HEXA polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7654
Background:
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Alternative Name:
Beta hexosaminidase alpha chain precursor, Beta hexosaminidase subunit alpha, Beta N acetylhexosaminidase, Beta N acetylhexosaminidase subunit alpha, Beta-hexosaminidase A, Beta-hexosaminidase subunit alpha, Beta-N-acetylhexosaminidase subunit alpha, Hexa, HEXA_HUMAN, Hexosaminidase A (alpha polypeptide), Hexosaminidase A alpha polypeptide, Hexosaminidase A, Hexosaminidase subunit A, MGC99608, N acetyl beta glucosaminidase, N acetyl beta glucosaminidase subunit alpha, N-acetyl-beta-glucosaminidase subunit alpha, TSD,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: HEXA polyclonal antibody detects endogenous levels of HEXA protein.
Immunogen:
Recombinant full length Human HEXA.
MW: ~60 kDa
Swis Prot.: P06865
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Alternative Name:
Beta hexosaminidase alpha chain precursor, Beta hexosaminidase subunit alpha, Beta N acetylhexosaminidase, Beta N acetylhexosaminidase subunit alpha, Beta-hexosaminidase A, Beta-hexosaminidase subunit alpha, Beta-N-acetylhexosaminidase subunit alpha, Hexa, HEXA_HUMAN, Hexosaminidase A (alpha polypeptide), Hexosaminidase A alpha polypeptide, Hexosaminidase A, Hexosaminidase subunit A, MGC99608, N acetyl beta glucosaminidase, N acetyl beta glucosaminidase subunit alpha, N-acetyl-beta-glucosaminidase subunit alpha, TSD,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: HEXA polyclonal antibody detects endogenous levels of HEXA protein.
Immunogen:
Recombinant full length Human HEXA.
MW: ~60 kDa
Swis Prot.: P06865
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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