HNMT Blocking Peptide (N-term)
€363.00
In stock
SKU
AC-BP1442A
Background:
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.
Other Names:
Histamine N-methyltransferase, HMT, HNMT
Target/Specificity:
The synthetic peptide sequence is selected from aa 44-58 of HUMAN HNMT
Gene Name: HNMT
Gene ID: 3176
Primary Accession: P50135
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.
Other Names:
Histamine N-methyltransferase, HMT, HNMT
Target/Specificity:
The synthetic peptide sequence is selected from aa 44-58 of HUMAN HNMT
Gene Name: HNMT
Gene ID: 3176
Primary Accession: P50135
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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