Hsp22 (HSPB8) Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP7139a
Background:
Heat-shock protein beta-8 (HSPB8) displays temperature-dependent chaperone activity. It acts as a Mn(2+)-dependent serine-threonine-specific protein kinase. Defects in HSPB8 are a cause of distal hereditary motor neuropathy type II ; also known as distal spinal muscular atrophy and spinal muscular atrophy of the Charcot-Marie-Tooth type. It is also an autosomal dominant disorder of lower motor neurons characterized by distal muscle weakness.
Other Names:
Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11, Small stress protein-like protein HSP22, HSPB8, CRYAC, E2IG1, HSP22
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7139a was selected from the N-term region of human HSPB8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HSPB8
Gene ID: 26353
Primary Accession: Q9UJY1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Heat-shock protein beta-8 (HSPB8) displays temperature-dependent chaperone activity. It acts as a Mn(2+)-dependent serine-threonine-specific protein kinase. Defects in HSPB8 are a cause of distal hereditary motor neuropathy type II ; also known as distal spinal muscular atrophy and spinal muscular atrophy of the Charcot-Marie-Tooth type. It is also an autosomal dominant disorder of lower motor neurons characterized by distal muscle weakness.
Other Names:
Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11, Small stress protein-like protein HSP22, HSPB8, CRYAC, E2IG1, HSP22
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7139a was selected from the N-term region of human HSPB8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HSPB8
Gene ID: 26353
Primary Accession: Q9UJY1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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