Human Creatine kinase muscle,CK-MMprotein
€0.00
In stock
SKU
BRP1101
Description: Recombinantcreatine kinasemuscle type,CK-MMProtein.
Background:
Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phospho-creatine kinase (and sometimes incorrectly as creatinine kinase), is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). This CK enzyme reaction is reversible and thus ATP can be generated from PCr and ADP. In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes: B on 14q32 and M on 19q13. In heart, in addition to the MM-CK homodimer also the heterodimer consisting of one muscle (MM-CK) and one brain-type (MB-CK) subunit is expressed. This latter is an important serum marker for myocardial infarction, for it is released from damaged myocardial cells into the blood where it can be detected by clinical chemistry.
Synonyms:
CKM, CKMM, creatine kinase M, Creatine kinase M type, creatine kinase muscle, creatine kinase muscle type, Creatine Kinase M-type, M-CK, MCK.
Purity: >90% by SDS-PAGE
Storage buffer: Each vial contains20 mM Tris-HCl pH8.0.
Storage and Expiration:
Ship at 4℃. Upon receipt, aliquot and store at -20℃ for long term. Avoid repeated freeze and thaw cycles.
Background:
Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phospho-creatine kinase (and sometimes incorrectly as creatinine kinase), is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). This CK enzyme reaction is reversible and thus ATP can be generated from PCr and ADP. In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes: B on 14q32 and M on 19q13. In heart, in addition to the MM-CK homodimer also the heterodimer consisting of one muscle (MM-CK) and one brain-type (MB-CK) subunit is expressed. This latter is an important serum marker for myocardial infarction, for it is released from damaged myocardial cells into the blood where it can be detected by clinical chemistry.
Synonyms:
CKM, CKMM, creatine kinase M, Creatine kinase M type, creatine kinase muscle, creatine kinase muscle type, Creatine Kinase M-type, M-CK, MCK.
Purity: >90% by SDS-PAGE
Storage buffer: Each vial contains20 mM Tris-HCl pH8.0.
Storage and Expiration:
Ship at 4℃. Upon receipt, aliquot and store at -20℃ for long term. Avoid repeated freeze and thaw cycles.
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