Human IL-2 recombinant active protein
€250.00
In stock
SKU
BT-C013
Background Information: Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
Target Name: Human Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2
Source:
Recombinant Human IL-2 (accession number P60568) (Ala21-Thr153) is expressed by E.coli expression system.
Molecular Weight:
The 133 amino acid protein has the predicted molecular weight of 15.5 kDa. The protein migrates at approximately 14 kDa on SDS-PAGE with DTT-reduced condition
Purity: >95% based on SDS-PAGE
Formulation: Lyophilized from a 0.2 μm filtered solution of 10mM sodium citrate, pH 4.0.
Bioactivity:
Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The specific activity of Recombinant Human IL-2 is ≥1×107 IU/mg.
Endotoxin level: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Reconstitution:
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage and Handling: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Target Name: Human Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2
Source:
Recombinant Human IL-2 (accession number P60568) (Ala21-Thr153) is expressed by E.coli expression system.
Molecular Weight:
The 133 amino acid protein has the predicted molecular weight of 15.5 kDa. The protein migrates at approximately 14 kDa on SDS-PAGE with DTT-reduced condition
Purity: >95% based on SDS-PAGE
Formulation: Lyophilized from a 0.2 μm filtered solution of 10mM sodium citrate, pH 4.0.
Bioactivity:
Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The specific activity of Recombinant Human IL-2 is ≥1×107 IU/mg.
Endotoxin level: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Reconstitution:
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage and Handling: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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