HUS1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP16922b
Background:
The protein encoded by this gene is a component of anevolutionarily conserved, genotoxin-activated checkpoint complexthat is involved in the cell cycle arrest in response to DNAdamage. This protein forms a heterotrimeric complex with checkpointproteins RAD9 and RAD1. In response to DNA damage, the trimericcomplex interacts with another protein complex consisting ofcheckpoint protein RAD17 and four small subunits of the replicationfactor C (RFC), which loads the combined complex onto thechromatin. The DNA damage induced chromatin binding has been shownto depend on the activation of the checkpoint kinase ATM, and isthought to be an early checkpoint signaling event. [provided byRefSeq].
Other Names:
Checkpoint protein HUS1, hHUS1, HUS1
Gene Name: HUS1
Gene ID: 3364
Primary Accession: O60921
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a component of anevolutionarily conserved, genotoxin-activated checkpoint complexthat is involved in the cell cycle arrest in response to DNAdamage. This protein forms a heterotrimeric complex with checkpointproteins RAD9 and RAD1. In response to DNA damage, the trimericcomplex interacts with another protein complex consisting ofcheckpoint protein RAD17 and four small subunits of the replicationfactor C (RFC), which loads the combined complex onto thechromatin. The DNA damage induced chromatin binding has been shownto depend on the activation of the checkpoint kinase ATM, and isthought to be an early checkpoint signaling event. [provided byRefSeq].
Other Names:
Checkpoint protein HUS1, hHUS1, HUS1
Gene Name: HUS1
Gene ID: 3364
Primary Accession: O60921
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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