JMJD8 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71630
Background:
JMJD8 (Jumonji domain-containing protein 8) is a 334 amino acid protein that contains one Jumonji domain and is expressed as 3 isoforms produced by alternative splicing. The gene that encodes JMJD8 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, making up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene, which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn’s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.
Alternative Name:
PP14397, C16orf20
Application Dilution: WB: 1:500 - 1:2000
Specificity: JMJD8 polyclonal antibody detects endogenous levels of JMJD8 protein.
Immunogen:
Recombinant protein of human JMJD8
MW: Predicted band size: 37 kDa, Observed band size: Refer to Figures
Swis Prot.: Q96S16
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
JMJD8 (Jumonji domain-containing protein 8) is a 334 amino acid protein that contains one Jumonji domain and is expressed as 3 isoforms produced by alternative splicing. The gene that encodes JMJD8 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, making up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene, which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn’s disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.
Alternative Name:
PP14397, C16orf20
Application Dilution: WB: 1:500 - 1:2000
Specificity: JMJD8 polyclonal antibody detects endogenous levels of JMJD8 protein.
Immunogen:
Recombinant protein of human JMJD8
MW: Predicted band size: 37 kDa, Observed band size: Refer to Figures
Swis Prot.: Q96S16
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review