KCNA4 Blocking Peptide (C-term)
€363.00
In stock
SKU
AC-BP19983b
Background:
Potassium channels represent the most complex class ofvoltage-gated ion channels from both functional and structuralstandpoints. Their diverse functions include regulatingneurotransmitter release, heart rate, insulin secretion, neuronalexcitability, epithelial electrolyte transport, smooth musclecontraction, and cell volume. Four sequence-related potassiumchannel genes - shaker, shaw, shab, and shal - have been identifiedin Drosophila, and each has been shown to have human homolog(s).This gene encodes a member of the potassium channel, voltage-gated,shaker-related subfamily. This member contains sixmembrane-spanning domains with a shaker-type repeat in the fourthsegment. It belongs to the A-type potassium current class, themembers of which may be important in the regulation of the fastrepolarizing phase of action potentials in heart and thus mayinflunce the duration of cardiac action potential. The codingregion of this gene is intronless, and the gene is clustered withgenes KCNA3 and KCNA10 on chromosome 1.
Other Names:
Potassium voltage-gated channel subfamily A member 4, HPCN2, Voltage-gated K(+) channel HuKII, Voltage-gated potassium channel HBK4, Voltage-gated potassium channel HK1, Voltage-gated potassium channel subunit Kv14, KCNA4, KCNA4L
Target/Specificity:
The synthetic peptide sequence is selected from aa 606-619 of HUMAN KCNA4
Gene Name: KCNA4
Gene ID: 3739
Primary Accession: P22459
Other Accession: P15385; Q61423; Q05037; NP_002224.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Potassium channels represent the most complex class ofvoltage-gated ion channels from both functional and structuralstandpoints. Their diverse functions include regulatingneurotransmitter release, heart rate, insulin secretion, neuronalexcitability, epithelial electrolyte transport, smooth musclecontraction, and cell volume. Four sequence-related potassiumchannel genes - shaker, shaw, shab, and shal - have been identifiedin Drosophila, and each has been shown to have human homolog(s).This gene encodes a member of the potassium channel, voltage-gated,shaker-related subfamily. This member contains sixmembrane-spanning domains with a shaker-type repeat in the fourthsegment. It belongs to the A-type potassium current class, themembers of which may be important in the regulation of the fastrepolarizing phase of action potentials in heart and thus mayinflunce the duration of cardiac action potential. The codingregion of this gene is intronless, and the gene is clustered withgenes KCNA3 and KCNA10 on chromosome 1.
Other Names:
Potassium voltage-gated channel subfamily A member 4, HPCN2, Voltage-gated K(+) channel HuKII, Voltage-gated potassium channel HBK4, Voltage-gated potassium channel HK1, Voltage-gated potassium channel subunit Kv14, KCNA4, KCNA4L
Target/Specificity:
The synthetic peptide sequence is selected from aa 606-619 of HUMAN KCNA4
Gene Name: KCNA4
Gene ID: 3739
Primary Accession: P22459
Other Accession: P15385; Q61423; Q05037; NP_002224.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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