MCP-3 human active recombinant protein

MCP-3 human active recombinant protein

€295.00
In stock
SKU
600150
Catalog Number: 600150
Size: 0.01 mg
Datasheet
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Protein Family: Cytokines

Pathway and Disease: Immune System, Signal Transduction, Signaling Molecules and Interaction

Alternate Names: C-C motif chemokine 7, small-inducible cytokin A7, monocyte chemoattractant protein 3, monocyte chemotactic protein 3, MCP-3, NC28, CCL7, MCP3, SCYA6, SCYA7Description:
Monocyte chemoattractant protein 3 (MCP-3 or C-C motif chemokine 7) is a chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. MCP-3 augments monocyte anti-tumor activity and increases the release of gelatinase B. MCP-3 binds to heparin, CCR1, CCR2, and CCR3. Recombinant Human MCP-3 produced in E. coli is a non-glycosylated polypeptide chain containing 76 amino acids with a MW of 9,011 Da.

Source: E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.

Applications: E, WB

Application Notes:
Human MCP-3 is fully biologically active when compared to standard. The specific activity as determined by the ability of MCP-3 to chemoattract human peripheral blood at 8 – 80 ng/ml.

Accession No.: P80098

MW: 9011 Da

Sequence:
QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL

Purity:
Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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