NDUFV1 Antibody(N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP19414a
Background:
The mitochondrial respiratory chain provides energy tocells via oxidative phosphorylation and consists of fourmembrane-bound electron-transporting protein complexes (I-IV) andan ATP synthase (complex V). This gene encodes a 51 kDa subunit ofthe NADH:ubiquinone oxidoreductase complex I; a large complex withat least 45 nuclear and mitochondrial encoded subunits thatliberates electrons from NADH and channels them to ubiquinone. Thissubunit carries the NADH-binding site as well as flavinmononucleotide (FMN)- and Fe-S-biding sites. Defects in complex Iare a common cause of mitochondrial dysfunction; a syndrome thatoccurs in approximately 1 in 10,000 live births. Mitochondrialcomplex I deficiency is linked to myopathies, encephalomyopathies,and neurodegenerative disorders such as Parkinson's disease andLeigh syndrome. Alternative splicing results in multiple transcriptvariants encoding distinct isoforms.
Other Names:
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, Complex I-51kD, CI-51kD, NADH dehydrogenase flavoprotein 1, NADH-ubiquinone oxidoreductase 51 kDa subunit, NDUFV1, UQOR1
Gene Name: NDUFV1 (HGNC:7716)
Gene ID: 4723
Primary Accession: P49821
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The mitochondrial respiratory chain provides energy tocells via oxidative phosphorylation and consists of fourmembrane-bound electron-transporting protein complexes (I-IV) andan ATP synthase (complex V). This gene encodes a 51 kDa subunit ofthe NADH:ubiquinone oxidoreductase complex I; a large complex withat least 45 nuclear and mitochondrial encoded subunits thatliberates electrons from NADH and channels them to ubiquinone. Thissubunit carries the NADH-binding site as well as flavinmononucleotide (FMN)- and Fe-S-biding sites. Defects in complex Iare a common cause of mitochondrial dysfunction; a syndrome thatoccurs in approximately 1 in 10,000 live births. Mitochondrialcomplex I deficiency is linked to myopathies, encephalomyopathies,and neurodegenerative disorders such as Parkinson's disease andLeigh syndrome. Alternative splicing results in multiple transcriptvariants encoding distinct isoforms.
Other Names:
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, Complex I-51kD, CI-51kD, NADH dehydrogenase flavoprotein 1, NADH-ubiquinone oxidoreductase 51 kDa subunit, NDUFV1, UQOR1
Gene Name: NDUFV1 (HGNC:7716)
Gene ID: 4723
Primary Accession: P49821
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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