Peroxin 3 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5849
Background:
Peroxin 3, also known as PEX3 (peroxisomal biogenesis factor 3) or TRG18, is a 373 amino acid multi-pass membrane protein that localizes to peroxisomes and belongs to the Peroxin family. Expressed ubiquitously, Peroxin 3 interacts with Peroxin 19 and is involved in peroxisome biosynthesis and membrane vesicle assembly, as well as in the maintenance of peroxisomal integrity. Additionally, Peroxin 3 acts as a docking factor for Peroxin 19 and is required for the import of peroxisomal proteins. Defects in the gene encoding Peroxin 3 are the cause of peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both of which arise from a failure of peroxisomal protein import.
Alternative Name:
Peroxisomal biogenesis factor 3, Peroxin-3, Peroxin3, Peroxisomal assembly protein PEX3, PEX3
Application Dilution: WB: 1:500~1:1000
Specificity: Peroxin 3 polyclonal antibody detects endogenous levels of Peroxin 3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 53-98 of Human Peroxin 3.
MW: ~ 42 kDa
Swis Prot.: P56589
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Peroxin 3, also known as PEX3 (peroxisomal biogenesis factor 3) or TRG18, is a 373 amino acid multi-pass membrane protein that localizes to peroxisomes and belongs to the Peroxin family. Expressed ubiquitously, Peroxin 3 interacts with Peroxin 19 and is involved in peroxisome biosynthesis and membrane vesicle assembly, as well as in the maintenance of peroxisomal integrity. Additionally, Peroxin 3 acts as a docking factor for Peroxin 19 and is required for the import of peroxisomal proteins. Defects in the gene encoding Peroxin 3 are the cause of peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both of which arise from a failure of peroxisomal protein import.
Alternative Name:
Peroxisomal biogenesis factor 3, Peroxin-3, Peroxin3, Peroxisomal assembly protein PEX3, PEX3
Application Dilution: WB: 1:500~1:1000
Specificity: Peroxin 3 polyclonal antibody detects endogenous levels of Peroxin 3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 53-98 of Human Peroxin 3.
MW: ~ 42 kDa
Swis Prot.: P56589
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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