PEX19 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14390a
Background:
This gene is necessary for early peroxisomal biogenesis.It acts both as a cytosolic chaperone and as an import receptor forperoxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteinsthat are essential for the assembly of functional peroxisomes. Theperoxisome biogenesis disorders (PBDs) are a group of geneticallyheterogeneous autosomal recessive, lethal diseases characterized bymultiple defects in peroxisome function. These disorders have atleast 14 complementation groups, with more than one phenotype beingobserved for some complementation groups. Although the clinicalfeatures of PBD patients vary, cells from all PBD patients exhibita defect in the import of one or more classes of peroxisomal matrixproteins into the organelle. Defects in this gene are a cause ofZellweger syndrome (ZWS), as well as peroxisome biogenesis disordercomplementation group 14 (PBD-CG14), which is also known asPBD-CGJ. Alternative splicing results in multiple transcriptvariants.
Other Names:
Peroxisomal biogenesis factor 19, 33 kDa housekeeping protein, Peroxin-19, Peroxisomal farnesylated protein, PEX19, HK33, PXF
Gene Name: PEX19 (HGNC:9713)
Gene ID: 5824
Primary Accession: P40855
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is necessary for early peroxisomal biogenesis.It acts both as a cytosolic chaperone and as an import receptor forperoxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteinsthat are essential for the assembly of functional peroxisomes. Theperoxisome biogenesis disorders (PBDs) are a group of geneticallyheterogeneous autosomal recessive, lethal diseases characterized bymultiple defects in peroxisome function. These disorders have atleast 14 complementation groups, with more than one phenotype beingobserved for some complementation groups. Although the clinicalfeatures of PBD patients vary, cells from all PBD patients exhibita defect in the import of one or more classes of peroxisomal matrixproteins into the organelle. Defects in this gene are a cause ofZellweger syndrome (ZWS), as well as peroxisome biogenesis disordercomplementation group 14 (PBD-CG14), which is also known asPBD-CGJ. Alternative splicing results in multiple transcriptvariants.
Other Names:
Peroxisomal biogenesis factor 19, 33 kDa housekeeping protein, Peroxin-19, Peroxisomal farnesylated protein, PEX19, HK33, PXF
Gene Name: PEX19 (HGNC:9713)
Gene ID: 5824
Primary Accession: P40855
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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