PSPB Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP11565b
Background:
This gene encodes the pulmonary-associated surfactantprotein B (SPB), an amphipathic surfactant protein essential forlung function and homeostasis after birth. Pulmonary surfactant isa surface-active lipoprotein complex composed of 90% lipids and 10%proteins which include plasma proteins and apolipoproteins SPA,SPB, SPC and SPD. The surfactant is secreted by the alveolar cellsof the lung and maintains the stability of pulmonary tissue byreducing the surface tension of fluids that coat the lung. The SPBenhances the rate of spreading and increases the stability ofsurfactant monolayers in vitro. Multiple mutations in this genehave been identified, which cause pulmonary surfactant metabolismdysfunction type 1, also called pulmonary alveolar proteinosis dueto surfactant protein B deficiency, and are associated with fatalrespiratory distress in the neonatal period. Alternatively splicedtranscript variants encoding the same protein have been identified.
Other Names:
Pulmonary surfactant-associated protein B, SP-B, 18 kDa pulmonary-surfactant protein, 6 kDa protein, Pulmonary surfactant-associated proteolipid SPL(Phe), SFTPB, SFTP3
Gene Name: SFTPB
Gene ID: 6439
Primary Accession: P07988
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes the pulmonary-associated surfactantprotein B (SPB), an amphipathic surfactant protein essential forlung function and homeostasis after birth. Pulmonary surfactant isa surface-active lipoprotein complex composed of 90% lipids and 10%proteins which include plasma proteins and apolipoproteins SPA,SPB, SPC and SPD. The surfactant is secreted by the alveolar cellsof the lung and maintains the stability of pulmonary tissue byreducing the surface tension of fluids that coat the lung. The SPBenhances the rate of spreading and increases the stability ofsurfactant monolayers in vitro. Multiple mutations in this genehave been identified, which cause pulmonary surfactant metabolismdysfunction type 1, also called pulmonary alveolar proteinosis dueto surfactant protein B deficiency, and are associated with fatalrespiratory distress in the neonatal period. Alternatively splicedtranscript variants encoding the same protein have been identified.
Other Names:
Pulmonary surfactant-associated protein B, SP-B, 18 kDa pulmonary-surfactant protein, 6 kDa protein, Pulmonary surfactant-associated proteolipid SPL(Phe), SFTPB, SFTP3
Gene Name: SFTPB
Gene ID: 6439
Primary Accession: P07988
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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