Recombinant human 17 beta-HSD8/HSD17B8 protein
€0.00
In stock
SKU
ATGP1001
Description
HSD17B8, also known as estradiol 17-beta-dehydrogenase 8, belongs to the short-chain dehydrogenases/reductases (SDR) family. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. It may play a role in biosynthesis of fatty acids in mitochondria. Recombinant human HSD17B8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.Alternative Names
Hydroxysteroid 17-beta dehydrogenase 8,(3R)-3-hydroxyacyl-CoA dehydrogenase, FABGL, HKE6, RING2, SDR30C1, 17-beta-hydroxysteroid dehydrogenase 8, 17-beta-HSD 8, HSD17B8, 3-ketoacyl-[acyl-carrier-protein, reductase alpha subunit, KAR alpha subunit, 3-oxoacyl-[acyl-carrier-protein, reductase, Estradiol 17-beta-dehydrogenase 8, Protein Ke6, Ke6, Short chain dehydrogenase/reductase family 30C member 1, Testosterone 17-beta-dehydrogenase 8, H2-KE6Concentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 150mM NaClStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
HSD17B8, also known as estradiol 17-beta-dehydrogenase 8, belongs to the short-chain dehydrogenases/reductases (SDR) family. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. It may play a role in biosynthesis of fatty acids in mitochondria. Recombinant human HSD17B8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.Alternative Names
Hydroxysteroid 17-beta dehydrogenase 8,(3R)-3-hydroxyacyl-CoA dehydrogenase, FABGL, HKE6, RING2, SDR30C1, 17-beta-hydroxysteroid dehydrogenase 8, 17-beta-HSD 8, HSD17B8, 3-ketoacyl-[acyl-carrier-protein, reductase alpha subunit, KAR alpha subunit, 3-oxoacyl-[acyl-carrier-protein, reductase, Estradiol 17-beta-dehydrogenase 8, Protein Ke6, Ke6, Short chain dehydrogenase/reductase family 30C member 1, Testosterone 17-beta-dehydrogenase 8, H2-KE6Concentration
0.5mg/ml (determined by Bradford assay)Concentration
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 150mM NaClStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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