SNRPN Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14532a
Background:
The protein encoded by this gene is one polypeptide of asmall nuclear ribonucleoprotein complex and belongs to the snRNPSMB/SMN family. The protein plays a role in pre-mRNA processing,possibly tissue-specific alternative splicing events. Althoughindividual snRNPs are believed to recognize specific nucleic acidsequences through RNA-RNA base pairing, the specific role of thisfamily member is unknown. The protein arises from a bicistronictranscript that also encodes a protein identified as the SNRPNupstream reading frame (SNURF). Multiple transcription initiationsites have been identified and extensive alternative splicingoccurs in the 5' untranslated region. Additional splice variantshave been described but sequences for the complete transcripts havenot been determined. The 5' UTR of this gene has been identified asan imprinting center. Alternative splicing or deletion caused by atranslocation event in this paternally-expressed region isresponsible for Angelman syndrome or Prader-Willi syndrome due toparental imprint switch failure.
Other Names:
Small nuclear ribonucleoprotein-associated protein N, snRNP-N, Sm protein D, Sm-D, Sm protein N, Sm-N, SmN, Tissue-specific-splicing protein, SNRPN, HCERN3, SMN
Gene Name: SNRPN
Gene ID: 6638;8926
Primary Accession: P63162
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is one polypeptide of asmall nuclear ribonucleoprotein complex and belongs to the snRNPSMB/SMN family. The protein plays a role in pre-mRNA processing,possibly tissue-specific alternative splicing events. Althoughindividual snRNPs are believed to recognize specific nucleic acidsequences through RNA-RNA base pairing, the specific role of thisfamily member is unknown. The protein arises from a bicistronictranscript that also encodes a protein identified as the SNRPNupstream reading frame (SNURF). Multiple transcription initiationsites have been identified and extensive alternative splicingoccurs in the 5' untranslated region. Additional splice variantshave been described but sequences for the complete transcripts havenot been determined. The 5' UTR of this gene has been identified asan imprinting center. Alternative splicing or deletion caused by atranslocation event in this paternally-expressed region isresponsible for Angelman syndrome or Prader-Willi syndrome due toparental imprint switch failure.
Other Names:
Small nuclear ribonucleoprotein-associated protein N, snRNP-N, Sm protein D, Sm-D, Sm protein N, Sm-N, SmN, Tissue-specific-splicing protein, SNRPN, HCERN3, SMN
Gene Name: SNRPN
Gene ID: 6638;8926
Primary Accession: P63162
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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