CD43 (SPN) polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8197
Background:
Over 100 cell surface markers have been identified through the use of monoclonal antibodies. Many of these markers have proven useful in identifying a specific subpopulation of cells within a mixed colony. Accordingly, these molecules have been assigned a “cluster of differentiation” (CD) designation. CD43 is the major O-glycosylated cell-surface associated sialoglycoprotein found on the cell membranes of leukocytes. It is a member of the surface mucin family which plays a central role in cellular adhesion tumor progression. Also called leukosialin, CD43 is best known as a marker for identifying normal and neoplastic T cells and a subset of neoplastic B cells within tissues. CD43 is thought to function as a negative regulator of cellular adhesion.
Alternative Name:
Leukosialin, Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, CD43, SPN, CD43
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: SPN polyclonal antibody detects endogenous levels of SPN protein.
Immunogen:
Recombinant full length Human SPN.
MW: ~ 40 kDa
Swis Prot.: P16150
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Over 100 cell surface markers have been identified through the use of monoclonal antibodies. Many of these markers have proven useful in identifying a specific subpopulation of cells within a mixed colony. Accordingly, these molecules have been assigned a “cluster of differentiation” (CD) designation. CD43 is the major O-glycosylated cell-surface associated sialoglycoprotein found on the cell membranes of leukocytes. It is a member of the surface mucin family which plays a central role in cellular adhesion tumor progression. Also called leukosialin, CD43 is best known as a marker for identifying normal and neoplastic T cells and a subset of neoplastic B cells within tissues. CD43 is thought to function as a negative regulator of cellular adhesion.
Alternative Name:
Leukosialin, Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, CD43, SPN, CD43
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: SPN polyclonal antibody detects endogenous levels of SPN protein.
Immunogen:
Recombinant full length Human SPN.
MW: ~ 40 kDa
Swis Prot.: P16150
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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