TARC human active recombinant protein

TARC human active recombinant protein

€295.00
In stock
SKU
600338
Catalog Number: 600338
Size: 0.02 mg
Datasheet
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Protein Family: Cytokines

Pathway and Disease: Infectious Diseases, Signaling Molecules and Interaction, Immune System

Alternate Names: CCL17, thymus and activation regulated chemokine, ABCD-2, SCYA18Description:
Thymus and activation regulated chemokine (TARC), also known as CCL17, is a chemokine produced by thymus tissue constitutively and activated PBMCs (mainly DCs). TARC signals through the CCR4 receptor to induce chemotaxis of Th2 cells. TARC is thought to be important in asthma and allergic diseases, along with bacterial and viral infections. Human TARC is produced in E.coli. Recombinant human TARC is a non-glycosylated protein, containing 71 amino acids, with a molecular weight of 8.1 kDa.

Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.

Applications: E, WB

Application Notes:
The activity can be determined by the ability to chemoattract human T cells at 2-40 ng/mL. There is no biological assay data available at this time. Specific activity: 5 x 10e5 units/mg

Accession No.: Q92583

MW: 8100 Da

Sequence:
ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S

Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Format:
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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