TPP1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7647
Background:
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Alternative Name:
Cell growth inhibiting gene 1 protein, Cell growth-inhibiting gene 1 protein, Ceroid lipofuscinosis neuronal 2, Ceroid lipofuscinosis neuronal 2 late infantile (Jansky Bielschowsky disease), Ceroid lipofuscinosis neuronal 2 late infantile, CLN 2, CLN2, GIG 1, GIG1, Growth inhibiting protein 1, LPIC, Lysosomal pepstatin insensitive protease, Lysosomal pepstatin-insensitive protease,MGC21297, TPP 1, TPP I, TPP-1, TPP-I, Tpp1, TPP1_HUMAN, TPPI, Tripeptidyl aminopeptidase, Tripeptidyl peptidase I, Tripeptidyl-peptidase 1, Tripeptidyl-peptidase I,
Application Dilution: WB: 1:500 - 1:2000
Specificity: TPP1 polyclonal antibody detects endogenous levels of TPP1 protein.
Immunogen:
Recombinant full length Human TPP1.
MW: ~61 kDa
Swis Prot.: O14773
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Alternative Name:
Cell growth inhibiting gene 1 protein, Cell growth-inhibiting gene 1 protein, Ceroid lipofuscinosis neuronal 2, Ceroid lipofuscinosis neuronal 2 late infantile (Jansky Bielschowsky disease), Ceroid lipofuscinosis neuronal 2 late infantile, CLN 2, CLN2, GIG 1, GIG1, Growth inhibiting protein 1, LPIC, Lysosomal pepstatin insensitive protease, Lysosomal pepstatin-insensitive protease,MGC21297, TPP 1, TPP I, TPP-1, TPP-I, Tpp1, TPP1_HUMAN, TPPI, Tripeptidyl aminopeptidase, Tripeptidyl peptidase I, Tripeptidyl-peptidase 1, Tripeptidyl-peptidase I,
Application Dilution: WB: 1:500 - 1:2000
Specificity: TPP1 polyclonal antibody detects endogenous levels of TPP1 protein.
Immunogen:
Recombinant full length Human TPP1.
MW: ~61 kDa
Swis Prot.: O14773
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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