ADAMTS2 antibody (clone 7G3), anti-human, rat
€435.00
In stock
SKU
AC-AT1049a
Catalog Number: AC-AT1049a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT1049a">Request Information
Background:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.
Other Names:
A disintegrin and metalloproteinase with thrombospondin motifs 2, ADAM-TS 2, ADAM-TS2, ADAMTS-2, Procollagen I N-proteinase, PC I-NP, Procollagen I/II amino propeptide-processing enzyme, Procollagen N-endopeptidase, pNPI, ADAMTS2, PCINP, PCPNI
Antigen Type:
Recombinant Protein
Gene Name: ADAMTS2
Gene ID: 9509
NCBI Accession: NP_055059.2;NP_067610.1
Primary Accession: O95450
Other Accession: NM_014244
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.
Other Names:
A disintegrin and metalloproteinase with thrombospondin motifs 2, ADAM-TS 2, ADAM-TS2, ADAMTS-2, Procollagen I N-proteinase, PC I-NP, Procollagen I/II amino propeptide-processing enzyme, Procollagen N-endopeptidase, pNPI, ADAMTS2, PCINP, PCPNI
Antigen Type:
Recombinant Protein
Gene Name: ADAMTS2
Gene ID: 9509
NCBI Accession: NP_055059.2;NP_067610.1
Primary Accession: O95450
Other Accession: NM_014244
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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