CALD1 Antibody (Center) Blocking Peptide

Background:
CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction.

Other Names:
Caldesmon, CDM, CALD1, CAD, CDM

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6609c was selected from the Center region of human CALD1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: CALD1

Gene ID: 800
Primary Accession: Q05682
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.