CFTR Peptide
€100.00
In stock
SKU
350548
Protein Family: Receptors and Channels, Transporters
Pathway and Disease: Membrane Transport, Metabolic Disorders
Alternate Names: Cystic fibrosis transmembrane conductance regulator; CFTR; cAMP-dependent chloride channel; ATP-binding cassette transporter sub-family C member 7; ABCC7
Accession No.: P13569, NP_000483
Description:
Cystic fibrosis transmembrane conductance regulator (CFTR), a ABC transporter, is involved in the transport of chloride ions and regulates bicarbonate secretion in epithelial cells by regulating the SLC4A7 transporter. CFTR is localized in aggresome bodies when proteasome's degradative capacity is exceeded and lysosomal degradation is engaged via autophagy. Defects in CFTR are the cause of cystic fibrosis.
Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 2238.5 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200186 is selected from a sequence within the N-term region of human CFTR. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C98H160N30O28S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Pathway and Disease: Membrane Transport, Metabolic Disorders
Alternate Names: Cystic fibrosis transmembrane conductance regulator; CFTR; cAMP-dependent chloride channel; ATP-binding cassette transporter sub-family C member 7; ABCC7
Accession No.: P13569, NP_000483
Description:
Cystic fibrosis transmembrane conductance regulator (CFTR), a ABC transporter, is involved in the transport of chloride ions and regulates bicarbonate secretion in epithelial cells by regulating the SLC4A7 transporter. CFTR is localized in aggresome bodies when proteasome's degradative capacity is exceeded and lysosomal degradation is engaged via autophagy. Defects in CFTR are the cause of cystic fibrosis.
Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 2238.5 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200186 is selected from a sequence within the N-term region of human CFTR. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C98H160N30O28S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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