CLCN7 Antibody (C-term) Blocking peptide

Background:
The product of this gene belongs to the CLC chloridechannel family of proteins. Chloride channels play important rolesin the plasma membrane and in intracellular organelles. This geneencodes chloride channel 7. Defects in this gene are the cause ofosteopetrosis autosomal recessive type 4 (OPTB4), also calledinfantile malignant osteopetrosis type 2 as well as the cause ofautosomal dominant osteopetrosis type 2 (OPTA2), also calledautosomal dominant Albers-Schonberg disease or marble diseaseautosoml dominant. Osteopetrosis is a rare genetic diseasecharacterized by abnormally dense bone, due to defective resorptionof immature bone. OPTA2 is the most common form of osteopetrosis,occurring in adolescence or adulthood.

Other Names:
H(+)/Cl(-) exchange transporter 7, Chloride channel 7 alpha subunit, Chloride channel protein 7, ClC-7, CLCN7

Gene Name: CLCN7 (HGNC:2025)

Gene ID: 1186
Primary Accession: P51798
Other Accession: NP_001278.1;NP_001107803.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.